Non-steroidal anti-inflammatory drugs (NSAIDs) are found to be effective in reducing pain and inflammation. Caution must be taken while using NSAIDs as overdosing can be toxic for the liver. Those with preexisting liver disease should be extremely careful while using them. NSAIDs cause a range of side effects, chances of which increase when used along with diuretics, angiotensin converting enzyme inhibitors, angiotensin 2 receptor blockers, anticoagulants or oral corticosteroids.